Details for gene set CL10567, PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS, AND URIDINE-DIPHOSPHATASE ACTIVITY[GSEA]

Table: GSEA Results Summary

Dataset	Medication for pain relief, constipation, heartburn__6154-both_sexes-4
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	CL10567, PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS, AND URIDINE-DIPHOSPHATASE ACTIVITY
Enrichment Score (ES)	0.56447184
Normalized Enrichment Score (NES)	1.1662376
Nominal p-value	0.16216215
FDR q-value	0.41707608
FWER p-Value	0.999

Fig 1: Enrichment plot: CL10567, PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS, AND URIDINE-DIPHOSPHATASE ACTIVITY
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ENTPD4	142	2.359	0.1637	Yes
2	GMPR	380	1.853	0.2854	Yes
3	PNP	596	1.620	0.3913	Yes
4	GMPS	1293	1.199	0.4400	Yes
5	IMPDH2	1308	1.195	0.5261	Yes
6	ENTPD8	1884	0.965	0.5645	Yes
7	ADK	4194	0.525	0.4748	No
8	IMPDH1	4306	0.513	0.5059	No
9	ITPA	5101	0.441	0.4940	No
10	PDE1C	5947	0.375	0.4745	No
11	CANT1	7060	0.304	0.4350	No
12	NT5E	7264	0.294	0.4452	No
13	ADSS2	8367	0.238	0.4014	No
14	AMPD2	9037	0.211	0.3798	No
15	ENTPD5	10171	0.171	0.3295	No
16	TPMT	10178	0.171	0.3415	No
17	AMPD1	10371	0.165	0.3429	No
18	ENTPD6	10628	0.157	0.3402	No
19	ENTPD1	10719	0.154	0.3464	No
20	AMPD3	11058	0.146	0.3383	No
21	PDE1B	11178	0.143	0.3421	No
22	ENPP3	11421	0.135	0.3386	No
23	APRT	12055	0.121	0.3123	No
24	ADSL	12793	0.104	0.2790	No
25	ENPP1	12851	0.102	0.2832	No
26	ENTPD3	13583	0.087	0.2491	No
27	PDE1A	16841	-0.000	0.0687	No
28	GDA	16880	-0.000	0.0666	No
29	HPRT1	17438	-0.000	0.0358	No

Fig 2: CL10567, PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS, AND URIDINE-DIPHOSPHATASE ACTIVITY: Random ES distribution
Gene set null distribution of ES for CL10567, PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS, AND URIDINE-DIPHOSPHATASE ACTIVITY